| 别名 | Inositol polyphosphate-5-phosphatase of 145 kDa; inositol polyphosphate-5-phosphatase, 145kDa; INPP5D; p150Ship; |
| 基因名称 | SHIP |
| 蛋白名称 | SHIP |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 3635 |
| Human Swissprot No. | Q92835 |
| Mouse Gene ID | 16331 |
| Mouse Swissprot No. | Q9ES52 |
| Rat Gene ID | 54259 |
| Rat Swissprot No. | P97573 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:2000 |
| 参考分子量 | MW(Observed):140kD |
| 预测分子量 | MW(Calculated):133kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | SHIP an SH2-containing inositol phosphatase. A hemopoietic-specific phosphatase that regulates cell survival, growth, cell cycle arrest and apoptosis. Hydrolyzes Ins(1,3,4,5)P4 and PtdIns(3,4,5)P3. A cytosolic protein with a SH2 domain in its N-terminus and two NPXY Shc binding motifs at its C-terminus. |
| 细胞定位 | Cytoplasm, Membrane, Peripheral membrane protein. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm, Membrane, Peripheral membrane protein. |
| 组织表达 | Spleen, Bone marrow, Liver, Lymphoma, Leukemia, Hepatocellular carcinoma. |
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