| 别名 | MCP; MIC10; TLX; TRA2.10; CD46; |
| 基因名称 | CD46 |
| 蛋白名称 | CD46 |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 4179 |
| Human Swissprot No. | P15529 |
| Mouse Swissprot No. | O88174 |
| Rat Swissprot No. | Q9Z0M4 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:2000 |
| 参考分子量 | MW(Observed):44kD |
| 预测分子量 | MW(Calculated):44kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | CD46 is a type I membrane protein and a regulatory part of the complement system. This protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, CD46 can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. |
| 细胞定位 | Cytoplasmic vesicle, Single-pass type I membrane protein, acrosome inner membrane, secretory vesicle. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasmic vesicle, Single-pass type I membrane protein, acrosome inner membrane, secretory vesicle. |
| 组织表达 | Widely expressed (Epithelium, Endothelium, Liver) |