| 别名 | GSF;IPF1;IUF1;IDX-1;MODY4;PDX-1;STF-1; |
| 基因名称 | PDX1 |
| 蛋白名称 | PDX1 |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 3651 |
| Human Swissprot No. | P52945 |
| Mouse Gene ID | 18609 |
| Mouse Swissprot No. | P52946 |
| Rat Gene ID | 29535 |
| Rat Swissprot No. | P52947 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:2000 |
| 参考分子量 | MW(Observed):42kD |
| 预测分子量 | MW(Calculated):31kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. |
| 细胞定位 | Cytoplasm, Nucleus, cytosol. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm, Nucleus, cytosol. |
| 组织表达 | Pancreas, Duodenum, Pancreatic cancer, Pancreatic neuroendocrine tumor, Colon cancer, Gastric cancer. |