| 别名 | MSH6; GTBP; HNPCC5; HSAP; p160; |
| 基因名称 | MSH6 |
| 蛋白名称 | MSH6 |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 2956 |
| Human Swissprot No. | P52701 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:2000 |
| 参考分子量 | MW(Observed):163kD |
| 预测分子量 | MW(Calculated):153kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The DNA mismatch repair system (MMR) repairs post-replication DNA, inhibits recombination between nonidentical DNA sequences, and induces both checkpoint and apoptotic responses following certain types of DNA damage. MSH2 (MutS homologue 2) forms the hMutS-α dimer with MSH6 and is an essential component of the mismatch repair process. |
| 细胞定位 | Cytosol, Golgi apparatus, Nucleoplasm, Nucleus. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytosol, Golgi apparatus, Nucleoplasm, Nucleus. |
| 组织表达 | Testis, Thymus, Bone marrow, Colorectal cancer, Endometrial cancer, Lung cancer. |