| 别名 | TLR2;CD282;TIL4;Toll-like receptor 2;Toll/interleukin-1 receptor-like protein 4; |
| 基因名称 | TLR2 |
| 蛋白名称 | TLR2 |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 7097 |
| Human Swissprot No. | O60603 |
| Mouse Swissprot No. | Q9QUN7 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:1000~1:2000 |
| 参考分子量 | MW(Observed):90kD |
| 预测分子量 | MW(Calculated):90kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Members of the Toll-like receptor (TLR) family, named for the closely related Toll receptor in Drosophila, play a pivotal role in innate immune responses (1-3). TLRs recognize conserved motifs found in various pathogens and mediate defense responses. Triggering of the TLR pathway leads to the activation of NF-κB and subsequent regulation of immune and inflammatory genes. |
| 细胞定位 | Membrane, Single-pass type I membrane protein. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Membrane, Single-pass type I membrane protein. |
| 组织表达 | Macrophages, Spleen, Lung, Inflammatory tissues, Lung cancer, Colon cancer. |
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