| 别名 | GCN2-like protein; GCN2; KIAA1338; EIF2AK4; |
| 基因名称 | Phospho-GCN2 (T899) |
| 蛋白名称 | Phospho-GCN2 (T899) |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 440275 |
| Human Swissprot No. | Q9P2K8 |
| Mouse Gene ID | 27103 |
| Mouse Swissprot No. | Q9QZ05 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:2000 |
| 参考分子量 | MW(Observed):220kD |
| 预测分子量 | MW(Calculated):187kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2. |
| 细胞定位 | cytosol, cytosolic ribosome. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Phospho |
| 细胞定位 | cytosol, cytosolic ribosome. |
| 组织表达 | Widely expressed (Liver, Kidney, Lung) |
周一至周日 8:00-18:00
