| 别名 | PKN2; PAK2; PRK2; Pak-2; PRKCL2; PRO2042; |
| 基因名称 | PKN2 |
| 蛋白名称 | PKN2 |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 5586 |
| Human Swissprot No. | Q16513 |
| Mouse Gene ID | 109333 |
| Mouse Swissprot No. | Q8BWW9 |
| Rat Swissprot No. | O08874 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:500~1:2000 |
| 参考分子量 | MW(Observed):112kD |
| 预测分子量 | MW(Calculated):112kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | PKC-related serine/threonine-protein kinase and Rho/Rac effector protein that participates in specific signal transduction responses in the cell. Plays a role in the regulation of cell cycle progression, actin cytoskeleton assembly, cell migration, cell adhesion, tumor cell invasion and transcription activation signaling processes. Phosphorylates CTTN in hyaluronan-induced astrocytes and hence decreases CTTN ability to associate with filamentous actin. |
| 细胞定位 | Apical junction complex, Centrosome, Cytoplasm, Cytosol, Intermediate filament cytoskeleton, Nuclear body, Nucleoplasm, Nucleus, Perinuclear region of cytoplasm, Plasma membrane. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Apical junction complex, Centrosome, Cytoplasm, Cytosol, Intermediate filament cytoskeleton, Nuclear body, Nucleoplasm, Nucleus, Perinuclear region of cytoplasm, Plasma membrane. |
| 组织表达 | Widely expressed (Brain, Liver, Lung) |