| 别名 | HDAC2; HD2; Histone deacetylase 2; RPD3; YAF1; YY1 associated factor 1; |
| 基因名称 | HDAC2 |
| 蛋白名称 | HDAC2 |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 3066 |
| Human Swissprot No. | Q92769 |
| Mouse Gene ID | 15182 |
| Mouse Swissprot No. | P70288 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:1000~1:2000 |
| 参考分子量 | MW(Observed):55kDa |
| 预测分子量 | MW(Calculated):55kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. |
| 细胞定位 | Nucleus, Cytoplasm. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Nucleus, Cytoplasm. |
| 组织表达 | Ubiquitous expression |
周一至周日 8:00-18:00
