| 别名 | CASP3; Caspase-3; APOPAIN; CPP32; CPP32B; SCA-1; |
| 基因名称 | pro Caspase 3 |
| 蛋白名称 | pro Caspase 3 |
| 推荐应用 | |
| 反应物种 | Human,Mouse |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 836 |
| Human Swissprot No. | P42574 |
| Mouse Gene ID | 12367 |
| Mouse Swissprot No. | P70677 |
| Rat Gene ID | 25402 |
| Rat Swissprot No. | P55213 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:2000 |
| 参考分子量 | MW(Observed):35kDa |
| 预测分子量 | MW(Calculated):32kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Caspase-3 (CPP-32, Apoptain, Yama, SCA-1) is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins such as the nuclear enzyme poly(ADP-ribose) polymerase (PARP). Activation of caspase-3 requires proteolytic processing of its inactive zymogen into activated p17 and p12 fragments. Cleavage of caspase-3 requires aspartic acid at the P1 position. |
| 细胞定位 | Cytoplasm. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm. |
| 组织表达 | Ubiquitous expression |
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