| 别名 | CR3A; MO1A; CD11B; MAC-1; MAC1A; SLEB6;ITGAM |
| 基因名称 | CD11b |
| 蛋白名称 | CD11b |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 3684 |
| Human Swissprot No. | P11215 |
| Mouse Swissprot No. | P05555 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 |
| 参考分子量 | MW(Observed):170kD |
| 预测分子量 | MW(Calculated):127kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | ITGAM, also named as CD11B and CR3A, belongs to the integrin alpha chain family. It is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. ITGAM is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. |
| 细胞定位 | Membrane |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Membrane |
| 组织表达 | Spleen, Bone marrow, Liver, Macrophages, Monocytes, Lymphoma. |