| 别名 | Low-density lipoprotein receptor-related protein 2; LRP-2; Glycoprotein 330; gp330; Megalin; LRP2; DBS; |
| 基因名称 | Lrp2 / Megalin |
| 蛋白名称 | Lrp2 / Megalin |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 4036 |
| Human Swissprot No. | P98164 |
| Mouse Swissprot No. | A2ARV4 |
| Rat Swissprot No. | P98158 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:2000 |
| 参考分子量 | MW(Observed):280kD |
| 预测分子量 | MW(Calculated):522kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | LRP2, also named as gp330 and Megalin, belongs to the LDLR family. It acts together with cubilin to mediate HDL endocytosis. LRP2 may participate in regulation of parathyroid-hormone and para-thyroid-hormone-related protein release. Defects in LRP2 are the cause of Donnai-Barrow syndrome (DBS). The antibody is specific to LRP2. |
| 细胞定位 | Apical cell membrane, Endosome lumen, Membrane, coated pit, Cell projection, dendrite, axon. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Apical cell membrane, Endosome lumen, Membrane, coated pit, Cell projection, dendrite, axon. |
| 组织表达 | Kidney, Lung, Brain, Renal cell carcinoma, Lung cancer, Glioma. |
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