| 别名 | Actin, aortic smooth muscle, Alpha-actin-2, Cell growth-inhibiting gene 46 protein, ACTA2, ACTSA, ACTVS, GIG46 |
| 基因名称 | alpha smooth muscle Actin |
| 蛋白名称 | alpha smooth muscle Actin |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 59 |
| Human Swissprot No. | P62736 |
| Mouse Gene ID | 11475 |
| Mouse Swissprot No. | P62737 |
| Rat Gene ID | 81633 |
| Rat Swissprot No. | P62738 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:1000~1:10000 |
| 参考分子量 | MW(Observed):42kD |
| 预测分子量 | MW(Calculated):42kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. They are primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance. |
| 细胞定位 | Cytoplasm. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm. |
| 组织表达 | Smooth muscle, Heart, Blood vessels, Leiomyosarcoma, Fibrosarcoma, Breast cancer. |
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