| 别名 | TACSTD2;GA733-1;M1S1;TROP2;Tumor-associated calcium signal transducer 2;Cell surface glycoprotein Trop-2;Membrane component chromosome 1 surface marker 1;Pancreatic carcinoma marker protein GA733-1 |
| 基因名称 | TROP-2 |
| 蛋白名称 | Tumor-associated calcium signal transducer 2 |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 4070 |
| Human Swissprot No. | P09758 |
| Mouse Gene ID | 56753 |
| Mouse Swissprot No. | Q8BGV3 |
| Rat Gene ID | 494343 |
| Rat Swissprot No. | Q6P9Z6 |
| 特异性 | endogenous |
| 稀释度 | WB 1:5000-1:20000;IF 1:50-1:200;ELISA 1:5000-1:20000; |
| 参考分子量 | MW(Observed):45-65kD |
| 预测分子量 | MW(Calculated):36kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.[provided by RefSeq, Dec 2009], |
| 细胞定位 | Membrane; Single-pass type I membrane protein. |
| 功能 | Disease:Defects in TACSTD2 are the cause of gelatinous drop-like corneal dystrophy (GDLD) [MIM:204870]; also known as lattice corneal dystrophy type III. GDLD is an autosomal recessive disorder characterized by grayish corneal amyloid deposits that cause severe visual impairment.,Function:GA733 tumor-associated antigen gene family may function as growth factor receptors.,PTM:The N-terminus is blocked.,similarity:Contains 1 thyroglobulin type-1 domain.,tissue specificity:Placenta, pancreatic carcinoma cell lines., |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Membrane; Single-pass type I membrane protein. |
| 组织表达 | Placenta, pancreatic carcinoma cell lines. |
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