| 别名 | DKK1;Dickkopf-related protein 1;Dickkopf-1;Dkk-1;hDkk-1;SK |
| 基因名称 | Dkk-1 |
| 蛋白名称 | Dickkopf-related protein 1 |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 22943 |
| Human Swissprot No. | O94907 |
| Mouse Gene ID | 13380 |
| Mouse Swissprot No. | O54908 |
| 特异性 | endogenous |
| 稀释度 | WB 1:1000-1:4000;IF 1:50-1:200;ELISA 1:5000-1:20000; |
| 参考分子量 | MW(Observed):28-40kD |
| 预测分子量 | MW(Calculated):29kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. [provided by RefSeq, Jul 2008], |
| 细胞定位 | Secreted. |
| 功能 | Function:Inhibitor of Wnt signaling pathway.,similarity:Belongs to the dickkopf family.,tissue specificity:Placenta., |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Secreted. |
| 组织表达 | Placenta. |
| 研究领域 | >>Wnt signaling pathway;>>Alzheimer disease;>>Pathways of neurodegeneration - multiple diseases |
周一至周日 8:00-18:00
