| 别名 | TOM40, C19orf1, D19S1177E, p38.5, PER EC1 |
| 基因名称 | TOMM40 |
| 蛋白名称 | Mitochondrial import receptor subunit TOM40 homolog (Protein Haymaker) (Translocase of outer membrane 40 kDa subunit homolog) (p38.5) |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 10452 |
| Human Swissprot No. | O96008 |
| Mouse Gene ID | 53333 |
| Mouse Swissprot No. | Q9QYA2 |
| Rat Gene ID | 308416 |
| Rat Swissprot No. | Q75Q40 |
| 特异性 | endogenous |
| 稀释度 | WB 1:500-1:2000;IF 1:50-1:200;ELISA 1:5000-1:20000;IP 1:50-1:200; |
| 参考分子量 | MW(Observed):38kD |
| 预测分子量 | MW(Calculated):38kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The protein encoded by this gene is localized in the outer membrane of the mitochondria. It is the channel-forming subunit of the translocase of the mitochondrial outer membrane (TOM) complex that is essential for import of protein precursors into mitochondria. Alternatively spliced transcript variants have been found for this gene. |
| 细胞定位 | Mitochondrion outer membrane ; Multi-pass membrane protein . Associates with the mitochondria-associated ER membrane via interaction with BCAP31. . |
| 功能 | Channel-forming protein essential for import of protein precursors into mitochondria . Plays a role in the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) by forming a complex with BCAP31 and mediating the translocation of Complex I components from the cytosol to the mitochondria . |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Mitochondrion outer membrane ; Multi-pass membrane protein . Associates with the mitochondria-associated ER membrane via interaction with BCAP31. . |
| 组织表达 | Heart, Skeletal muscle, Liver, Kidney, Hepatocellular carcinoma, Colon cancer, Lung cancer |
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