| 别名 | NBEAL2;KIAA0540;UNQ253/PRO290;Neurobeachin-like protein 2; |
| 基因名称 | NBEAL2 |
| 蛋白名称 | Neurobeachin-like protein 2 |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 23218 |
| Human Swissprot No. | Q6ZNJ1 |
| 特异性 | endogenous |
| 稀释度 | WB 1:1000-1:2500; |
| 参考分子量 | MW(Observed):303kD |
| 预测分子量 | MW(Calculated):303kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The protein encoded by this gene contains a beige and Chediak-Higashi (BEACH) domain and multiple WD40 domains , and may play a role in megakaryocyte alpha-granule biogenesis. Mutations in this gene are a cause of gray platelet syndrome. |
| 细胞定位 | Endoplasmic reticulum. |
| 功能 | Probably involved in thrombopoiesis. Plays a role in the development or secretion of alpha-granules, that contain several growth factors important for platelet biogenesis. {ECO:0000269|PubMed:21765411, ECO:0000269|PubMed:21765412}. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Endoplasmic reticulum. |
| 组织表达 | Expressed in megakaryocytes. {ECO:0000269|PubMed:21765411}. |