| 别名 | Glutamate receptor, ionotropic kainate 4;Excitatory amino acid receptor 1;EAA1;Glutamate receptor KA-1;KA1; |
| 基因名称 | KA1 |
| 蛋白名称 | GRIK4 |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 2900 |
| Human Swissprot No. | Q16099 |
| Mouse Gene ID | 110637 |
| Mouse Swissprot No. | Q8BMF5 |
| Rat Gene ID | 24406 |
| Rat Swissprot No. | Q01812 |
| 特异性 | endogenous |
| 稀释度 | WB 1:1000-1:2500; |
| 参考分子量 | MW(Observed):105kDa |
| 预测分子量 | MW(Calculated):105kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013], |
| 细胞定位 | Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. |
| 功能 | Function:Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists.,similarity:Belongs to the glutamate-gated ion channel (TC 1.A.10) family.,subunit:Forms a heteromeric channel with GRIK1 or GRIK3., |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. |
| 组织表达 | Hippocampus,Kidney, |
| 研究领域 | >>Neuroactive ligand-receptor interaction;>>Glutamatergic synapse |
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