| 别名 | BDNF precursor form, brain derived neurotrophic factor, Brain-derived neurotrophic factor |
| 基因名称 | BDNF |
| 蛋白名称 | BDNF |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 627 |
| Human Swissprot No. | P23560 |
| Mouse Swissprot No. | P21237 |
| Rat Swissprot No. | P23363 |
| 特异性 | endogenous |
| 稀释度 | IHC 1:2000-1:10000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200; |
| 参考分子量 | MW(Observed):Precursor 28kD,Mature 12-14kD |
| 预测分子量 | MW(Calculated):28kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants , at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's , Parkinson's , and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders. |
| 细胞定位 | Secreted |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Secreted |
| 组织表达 | Brain, Spinal cord, Retina, Glioma, Neuroblastoma, Medulloblastoma |