| 别名 | FOXA1;HNF3A;TCF3A;Hepatocyte nuclear factor 3-alpha;HNF-3-alpha;HNF-3A;Forkhead box protein A1;Transcription factor 3A;TCF-3A; |
| 基因名称 | FOXA1 |
| 蛋白名称 | Hepatocyte nuclear factor 3-alpha |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat, |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 3169 |
| Human Swissprot No. | P55317 |
| Mouse Gene ID | 15375 |
| Mouse Swissprot No. | P35582 |
| Rat Gene ID | 25098 |
| Rat Swissprot No. | P23512 |
| 特异性 | endogenous |
| 稀释度 | IHC 1:200-1:1000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200; |
| 参考分子量 | MW(Observed):49kD |
| 预测分子量 | MW(Calculated):49kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. [provided by RefSeq, Jul 2008], |
| 细胞定位 | Nucleus |
| 功能 | Function:Transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes.,online information:Hepatocyte nuclear factors entry,similarity:Contains 1 fork-head DNA-binding domain., |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Nucleus |
| 组织表达 | Highly expressed in prostate and ESR1-positive breast tumors. Overexpressed in esophageal and lung adenocarcinomas. |
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