| 别名 | Thrombospondin-1 |
| 基因名称 | THBS1 |
| 蛋白名称 | Thrombospondin 1 |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 7057 |
| Human Swissprot No. | P07996 |
| 特异性 | endogenous |
| 稀释度 | WB 1:1000-1:5000；ELISA 1:5000-1:20000 |
| 参考分子量 | MW(Observed):170kD |
| 预测分子量 | MW(Calculated):130kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | thrombospondin 1(THBS1) Homo sapiens The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis. [provided by RefSeq, Jul 2008], |
| 细胞定位 | Secreted |
| 功能 | Function:Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1, alpha-V/beta-3 and alpha-IIb/beta-3.,similarity:Belongs to the thrombospondin family.,similarity:Contains 1 TSP C-terminal (TSPC) domain.,similarity:Contains 1 TSP N-terminal (TSPN) domain.,similarity:Contains 1 VWFC domain.,similarity:Contains 3 EGF-like domains.,similarity:Contains 3 TSP type-1 domains.,similarity:Contains 8 TSP type-3 repeats.,subunit:Homotrimer; disulfide-linked., |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Secreted |
| 组织表达 | Aorta endothelial cell,Endothelial cell,Liver,Plasma,Platelet,Saliva, |
| 研究领域 | >>Rap1 signaling pathway;>>p53 signaling pathway;>>Phagosome;>>PI3K-Akt signaling pathway;>>TGF-beta signaling pathway;>>Focal adhesion;>>ECM-receptor interaction;>>Malaria;>>Human papillomavirus infection;>>Proteoglycans in cancer;>>MicroRNAs in cancer;>>Bladder cancer |
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