| 别名 | CDC42; CDC42Hs; G25K; TKS; |
| 基因名称 | CDC42 |
| 蛋白名称 | CDC42 |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 998 |
| Human Swissprot No. | P60953 |
| Mouse Swissprot No. | P60766 |
| Rat Swissprot No. | Q8CFN2 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:1000~1:2000 |
| 参考分子量 | MW(Observed):21kD |
| 预测分子量 | MW(Calculated):21kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Rac and Cdc42 are members of the Rho-GTPase family. In mammals, Rac exists as three isoforms, Rac1, Rac2 and Rac3, which are highly similar in sequence. Rac1 and Cdc42, the most widely studied of this group, are ubiquitously expressed. Rac and Cdc42 play key signaling roles in cytoskeletal reorganization, membrane trafficking, transcriptional regulation, cell growth and development. |
| 细胞定位 | Cell membrane, Cytoplasm, Cytoplasmic side, Lipid-anchor, Midbody, centrosome, cytoskeleton, microtubule organizing center, spindle. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cell membrane, Cytoplasm, Cytoplasmic side, Lipid-anchor, Midbody, centrosome, cytoskeleton, microtubule organizing center, spindle. |
| 组织表达 | Widely expressed (Brain, Liver, Lung) |