| 别名 | DIRA; ICIL1RA; IL-1ra; IL-1ra3; IL-1RN; IL1 inhibitor; IL1F3; IL1RN (IL1F3); Interleukin-1 receptor antagonist protein; IRAP; Type II interleukin 1 receptor antagonist; |
| 基因名称 | IL1RA |
| 蛋白名称 | IL1RA |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 3557 |
| Human Swissprot No. | P18510 |
| Mouse Gene ID | 16181 |
| Mouse Swissprot No. | P25085 |
| Rat Gene ID | 60582 |
| Rat Swissprot No. | P25086 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:5000~1:20000 |
| 参考分子量 | MW(Observed):20kD |
| 预测分子量 | MW(Calculated):20kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Interleukin-1 (IL-1) is a key pro-inflammatory cytokine that has diverse actions in the brain as a regulator of host defense responses and a mediator of inflammation. Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. |
| 细胞定位 | Cytoplasm, Secreted. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm, Secreted. |
| 组织表达 | Liver, Spleen, Lung, Hepatocellular carcinoma, Lung cancer, Colon cancer. |