| 别名 | PLC-148; PLC-II; PLC-gamma1; PLC1; PLCG-1; Phospholipase C-gamma-1; |
| 基因名称 | PLC gamma 1 |
| 蛋白名称 | PLC gamma 1 |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 5335 |
| Human Swissprot No. | P19174 |
| Mouse Gene ID | 18803 |
| Mouse Swissprot No. | Q62077 |
| Rat Gene ID | 25738 |
| Rat Swissprot No. | P10686 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:1000~1:5000 |
| 参考分子量 | MW(Observed):149kD |
| 预测分子量 | MW(Calculated):149kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. |
| 细胞定位 | Cell projection, lamellipodium, ruffle. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cell projection, lamellipodium, ruffle. |
| 组织表达 | Widely expressed (Brain, Liver, Lung) |
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