| 别名 | ERN1, ER to nucleus signalling 1, Inositol-requiring enzyme 1, Inositol-requiring protein 1, Ire1-alpha, IRE1a, HIRE1p, IRE1, Inositol-requiring 1, IRE1P; |
| 基因名称 | Phospho-IRE1 (S724) |
| 蛋白名称 | Phospho-IRE1 (S724) |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 2081 |
| Human Swissprot No. | O75460 |
| Mouse Gene ID | 78943 |
| Mouse Swissprot No. | Q9EQY0 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:2000 |
| 参考分子量 | MW(Observed):110kD |
| 预测分子量 | MW(Calculated):110kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis. |
| 细胞定位 | Endoplasmic reticulum membrane, Single-pass type I membrane protein. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Phospho |
| 细胞定位 | Endoplasmic reticulum membrane, Single-pass type I membrane protein. |
| 组织表达 | Widely expressed (Liver, Kidney, Lung) |
周一至周日 8:00-18:00
