| 别名 | CK-10; CK10; cytokeratin 10; Cytokeratin-10; K10; K1C10; keratin 10; Keratin, type I cytoskeletal 10; Keratin-10; KPP; KRT10; |
| 基因名称 | Cytokeratin 10 |
| 蛋白名称 | Cytokeratin 10 |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 3858 |
| Human Swissprot No. | P13645 |
| Mouse Gene ID | 16661 |
| Mouse Swissprot No. | P02535 |
| Rat Gene ID | 450225 |
| Rat Swissprot No. | Q6IFW6 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 |
| 参考分子量 | MW(Observed):60kD |
| 预测分子量 | MW(Calculated):59kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | K10 a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. There are two types of cytoskeletal and microfibrillar keratin: type I (acidic; 40-55 kDa) [K9 to K20] and type II (neutral to basic; 56-70 kDa) [K1 to K8]. Both a basic and an acidic keratin are required for filament assembly. |
| 细胞定位 | Secreted , extracellular space . Cell surface . Localized on the surface of desquamated nasal epithelial cells. Localized on the surface of lung cell lines. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Secreted , extracellular space . Cell surface . Localized on the surface of desquamated nasal epithelial cells. Localized on the surface of lung cell lines. |
| 组织表达 | Skin, Esophagus, Tongue, Squamous cell carcinoma, Basal cell carcinoma, Cervical cancer. |