| 别名 | C358B7.1; P18; UBC9; UBE2I; SUMO1 protein ligase; |
| 基因名称 | UBE2I |
| 蛋白名称 | UBE2I |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 7329 |
| Human Swissprot No. | P63279 |
| Mouse Gene ID | 100044900 |
| Mouse Swissprot No. | P63280 |
| Rat Gene ID | 25573 |
| Rat Swissprot No. | P63281 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:500~1:2000 |
| 参考分子量 | MW(Observed):18kD |
| 预测分子量 | MW(Calculated):18kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The process of SUMO-1 conjugation is similar to that seen with ubiquitin and other forms of post-translational protein modification. Like ubiquitin, SUMO-1 is conjugated to its target protein by the coordinated action of ubiquitin conjugation enzymes E1, E2 and E3. Ubc9 (or ube2M) is a highly conserved, 158 amino acid protein that acts as a SUMO-1 conjugating enzyme. Ubc9 binds to target proteins through their SUMO-1-CS (consensus sequence) domains and interacts with SUMO via the structurally conserved amino-terminal domain. |
| 细胞定位 | Cytoplasm. Nucleus. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm. Nucleus. |
| 组织表达 | Widely expressed (Testis, Thymus, Bone marrow) |
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