| 别名 | OSIL; Oxidative stress induced like; p60; p62; p62B; Paget disease of bone 3;PDB 3; PDB3; |
| 基因名称 | p62/SQSTM1 |
| 蛋白名称 | p62/SQSTM1 |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 8878 |
| Human Swissprot No. | Q13501 |
| Mouse Gene ID | 18412 |
| Mouse Swissprot No. | Q64337 |
| Rat Gene ID | 113894 |
| Rat Swissprot No. | O08623 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:5000~1:10000 |
| 参考分子量 | MW(Observed):62kD |
| 预测分子量 | MW(Calculated):48kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the autophagic machinery. Involved in midbody ring degradation. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. |
| 细胞定位 | Cytoplasm, Cytoplasmic vesicle, Endoplasmic reticulum, Late endosome, Lysosome, Nucleus, P-body, autophagosome. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm, Cytoplasmic vesicle, Endoplasmic reticulum, Late endosome, Lysosome, Nucleus, P-body, autophagosome. |
| 组织表达 | Liver, Kidney, Brain, Hepatocellular carcinoma, Lung cancer, Colon cancer, Breast cancer. |
周一至周日 8:00-18:00
