| 别名 | HRMT1L5; IBP72; JBP1; SKB1; SKB1Hs; PRMT5; Skb1Hs Methyltransferase; |
| 基因名称 | PRMT5 |
| 蛋白名称 | PRMT5 |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 10419 |
| Human Swissprot No. | O14744 |
| Mouse Swissprot No. | Q8CIG8 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:5000~1:10000 |
| 参考分子量 | MW(Observed):73kDa |
| 预测分子量 | MW(Calculated):73kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Involved in regulation of cell cycle progression through G2 by negatively regulating Swe1p, a protein tyrosine kinase that phosphorylates and inhibits Cdc28p. An Hsl7p homologue, Skb1, was identified in fission yeast by virtue of its yeast two-hybrid interaction with Shk1p, a p21 (cdc42p/Rac) activated kinase (PAK). |
| 细胞定位 | Cytoplasm, Nucleus, Golgi apparatus, Chromosome. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm, Nucleus, Golgi apparatus, Chromosome. |
| 组织表达 | Ubiquitous expression |