| 别名 | NAK; T2K; NF-kappa-B-activating kinase; TANK-binding kinase 1; Serine/threonine-protein kinase TBK1; T2K; TANK binding kinase 1; |
| 基因名称 | NAK/TBK1 (N-term) |
| 蛋白名称 | NAK/TBK1 (N-term) |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 29110 |
| Human Swissprot No. | Q9UHD2 |
| Mouse Gene ID | 56480 |
| Mouse Swissprot No. | Q9WUN2 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:2000 |
| 参考分子量 | MW(Observed):84kD |
| 预测分子量 | MW(Calculated):84kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. |
| 细胞定位 | Cytoplasm. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm. |
| 组织表达 | Widely expressed (Spleen, Liver, Lung) |