| 别名 | eplication protein C; PP2A-alpha; Replication protein C; RP-C; PPP2CA; MGC786 |
| 基因名称 | Phospho-PP2A alpha (Y307) |
| 蛋白名称 | Phospho-PP2A alpha (Y307) |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 5515 |
| Human Swissprot No. | P67775 |
| Mouse Gene ID | 19052 |
| Mouse Swissprot No. | P63330 |
| Rat Gene ID | 24672 |
| Rat Swissprot No. | P63331 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:2000 |
| 参考分子量 | MW(Observed):35kD |
| 预测分子量 | MW(Calculated):36kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'. |
| 细胞定位 | Cytoplasm, Nucleus, Chromosome, centromere, cytoskeleton, spindle pole. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Phospho |
| 细胞定位 | Cytoplasm, Nucleus, Chromosome, centromere, cytoskeleton, spindle pole. |
| 组织表达 | Widely expressed (Brain, Liver, Lung) |
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