| 别名 | glycogen synthase kinase 3 beta; Glycogen synthase kinase-3 beta; GSK-3 beta; GSK3B; GSK3beta isoform; |
| 基因名称 | GSK3 beta |
| 蛋白名称 | GSK3 beta |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 2932 |
| Human Swissprot No. | P49841 |
| Mouse Gene ID | 56637 |
| Mouse Swissprot No. | Q9WV60 |
| Rat Gene ID | 84027 |
| Rat Swissprot No. | P18266 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:3000 |
| 参考分子量 | MW(Observed):46kD |
| 预测分子量 | MW(Calculated):47kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase .GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation.In skeletal muscle, it contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. |
| 细胞定位 | Cytoplasm, Nucleus, Cell membrane |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm, Nucleus, Cell membrane |
| 组织表达 | Widely expressed (Brain, Liver, Heart) |