| 别名 | ADORA1;Adenosine receptor A1 |
| 基因名称 | Adenosine A1-R |
| 蛋白名称 | Adenosine receptor A1 |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 134 |
| Human Swissprot No. | P30542 |
| Mouse Swissprot No. | Q60612 |
| Rat Gene ID | 29290 |
| Rat Swissprot No. | P25099 |
| 特异性 | endogenous |
| 稀释度 | WB 1:1000-1:4000;IF 1:50-1:200;ELISA 1:5000-1:20000;IP 1:50-1:200; |
| 参考分子量 | MW(Observed):37kD |
| 预测分子量 | MW(Calculated):37kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene. [provided by RefSeq, Jul 2008], |
| 细胞定位 | Cell membrane ; Multi-pass membrane protein. |
| 功能 | Function:Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.,similarity:Belongs to the G-protein coupled receptor 1 family., |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cell membrane ; Multi-pass membrane protein. |
| 组织表达 | Brain,Heart,Hippocampus, |
| 研究领域 | >>cGMP-PKG signaling pathway;>>cAMP signaling pathway;>>Sphingolipid signaling pathway;>>Neuroactive ligand-receptor interaction;>>Regulation of lipolysis in adipocytes;>>Renin secretion;>>Morphine addiction |
周一至周日 8:00-18:00
