| 别名 | STARD4;StAR-related lipid transfer protein 4 ;START domain-containing protein 4;StARD4; |
| 基因名称 | STARD4 |
| 蛋白名称 | StAR-related lipid transfer protein 4;START domain-containing protein 4;StARD4; |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 134429 |
| Human Swissprot No. | Q96DR4 |
| 特异性 | endogenous |
| 稀释度 | WB 1:1000-1:2500； |
| 参考分子量 | MW(Observed):23kD |
| 预测分子量 | MW(Calculated):23kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Cholesterol homeostasis is regulated , at least in part , by sterol regulatory element (SRE) -binding proteins (e.g. , SREBP1; MIM 184756) and by liver X receptors (e.g. , LXRA; MIM 602423) . Upon sterol depletion , LXRs are inactive and SREBPs are cleaved , after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers , such as steroidogenic acute regulatory protein (STAR; MIM 600617) . STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain , including STARD4 |
| 细胞定位 | cytoplasm,cytoplasmic vesicle,cytosol,endoplasmic |
| 功能 | Involved in the intracellular transport of cholesterol. Binds cholesterol or other sterols. {ECO:0000269|PubMed:18403318}. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | cytoplasm,cytoplasmic vesicle,cytosol,endoplasmic |
| 组织表达 | Liver, Kidney, Adrenal gland, Hepatocellular carcinoma, Renal cell carcinoma, Lung cancer |
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