| 别名 | RBMY1A1;RBM1;RBM2;YRRM1;YRRM2;RNA-binding motif protein, Y chromosome, family 1 member A1 ;RNA-binding motif protein 1;RNA-binding motif protein 2;Y chromosome RNA recognition motif 1;hRBMY; |
| 基因名称 | RBMY1A1 |
| 蛋白名称 | RNA-binding motif protein, Y chromosome, family 1 member A1;RNA-binding motif protein 1;RNA-binding motif protein 2;Y chromosome RNA recognition motif 1;hRBMY; |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 5940 |
| Human Swissprot No. | P0DJD3 |
| Mouse Gene ID | 100862365 |
| Mouse Swissprot No. | O35698 |
| 特异性 | endogenous |
| 稀释度 | WB 1:1000-1:2500； |
| 参考分子量 | MW(Observed):55kD |
| 预测分子量 | MW(Calculated):55kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine , arginine , glycine , tyrosine) boxes in the C-terminus. This protein is thought to function as a splicing regulator during spermatogenesis. Multiple closely related paralogs of this gene are found in a gene cluster in the AZFb azoospermia factor region of chromosome Y. Most of these related copies are thought to be pseudogenes , though several likely encode functional proteins. |
| 细胞定位 | Nucleus. |
| 功能 | RNA-binding protein involved in pre-mRNA splicing. Required for sperm development. Acts additively with TRA2B to promote exon 7 inclusion of the survival motor neuron SMN. Binds non-specifically to mRNAs. {ECO:0000269|PubMed:12165565, ECO:0000269|PubMed:8269511}. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Nucleus. |
| 组织表达 | Testis-specific. {ECO:0000269|PubMed:8269511}. |
周一至周日 8:00-18:00
