| 别名 | KIAA0094, METAP1, Methionine aminopeptidase 1, MAP 1, MetAP 1, Peptidase M 1 |
| 基因名称 | Methionyl Aminopeptidase 1 |
| 蛋白名称 | Methionine aminopeptidase 1 (MAP 1) (MetAP 1) (Peptidase M 1) |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 23173 |
| Human Swissprot No. | P53582 |
| Mouse Swissprot No. | Q8BP48 |
| 特异性 | endogenous |
| 稀释度 | WB 1:1000-1:2500;FC 1:100-1:500; |
| 参考分子量 | MW(Observed):42kDa |
| 预测分子量 | MW(Calculated):42kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | catalytic activity:Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.,cofactor:Binds 1 sodium ion per subunit. The sodium ion has a structural role.,cofactor:Binds 2 cobalt ions per subunit.,cofactor:Binds 2 cobalt ions per subunit. The true nature of the physiological cofactor is under debate. The enzyme is also active with zinc, manganese or divalent iron ions.,function:Removes the amino-terminal methionine from nascent proteins.,function:Removes the amino-terminal methionine from nascent proteins. Required for normal progression through the cell cycle.,similarity:Belongs to the peptidase M24A family., |
| 细胞定位 | Cytoplasm . |
| 功能 | Catalytic activity:Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.,cofactor:Binds 1 sodium ion per subunit. The sodium ion has a structural role.,cofactor:Binds 2 cobalt ions per subunit.,cofactor:Binds 2 cobalt ions per subunit. The true nature of the physiological cofactor is under debate. The enzyme is also active with zinc, manganese or divalent iron ions.,Function:Removes the amino-terminal methionine from nascent proteins.,Function:Removes the amino-terminal methionine from nascent proteins. Required for normal progression through the cell cycle.,similarity:Belongs to the peptidase M24A family., |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm . |
| 组织表达 | Bone marrow,Placenta,Testis, |
周一至周日 8:00-18:00
