| 别名 | ZW10-interacting kinetochore protein、Zwint-1、ZW10 interactor、KNTC2AP、ZW10-interacting protein 1 |
| 基因名称 | ZWINT |
| 蛋白名称 | ZW10 interactor (ZW10-interacting protein 1) (Zwint-1) |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 11130 |
| Human Swissprot No. | O95229 |
| Mouse Gene ID | 52696 |
| Mouse Swissprot No. | Q9CQU5 |
| Rat Gene ID | 52696 |
| Rat Swissprot No. | Q8VIL3 |
| 特异性 | endogenous |
| 稀释度 | WB 1:1000-1:2500;FC 1:100-1:500; |
| 参考分子量 | MW(Observed):30kDa |
| 预测分子量 | MW(Calculated):30kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| 细胞定位 | Nucleus. Chromosome, centromere, kinetochore. Localizes to kinetochores from late prophase to anaphase. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Nucleus. Chromosome, centromere, kinetochore. Localizes to kinetochores from late prophase to anaphase. |
| 组织表达 | Testis, Thymus, Bone marrow, Lung cancer, Colon cancer, Breast cancer |
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