| 别名 | Killin, KLLN |
| 基因名称 | KLLN |
| 蛋白名称 | KILIN |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 100144748 |
| Human Swissprot No. | B2CW77 |
| 特异性 | endogenous |
| 稀释度 | WB 1:1000-1:2500; |
| 参考分子量 | MW(Observed):20kDa |
| 预测分子量 | MW(Calculated):20kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The protein encoded by this intronless gene is found in the nucleus, where it can inhibit DNA synthesis and promote S phase arrest coupled to apoptosis. The expression of this DNA binding protein is upregulated by transcription factor p53. [provided by RefSeq, Dec 2012], |
| 细胞定位 | Nucleus . |
| 功能 | Function:DNA-binding protein involved in S phase checkpoint control-coupled apoptosis by mediating p53/TP53-induced apoptosis. Has the ability to inhibit DNA synthesis and S phase arrest coupled to apoptosis. Has affinity to both double- and single-stranded DNA.,induction:by p53/TP53; direct transcription target of p53/TP53., |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Nucleus . |
| 组织表达 | Kidney, Liver, Lung, Renal cell carcinoma, Lung cancer, Breast cancer |
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