| 别名 | Lipoma HMGIC fusion partner-like 5、TMHS、Tetraspan membrane protein of hair cell stereocilia |
| 基因名称 | LHFPL5 |
| 蛋白名称 | Tetraspan membrane protein of hair cell stereocilia (Lipoma HMGIC fusion partner-like 5 protein) |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 222662 |
| Human Swissprot No. | Q8TAF8 |
| Mouse Gene ID | 328789 |
| Mouse Swissprot No. | Q4KL25 |
| Rat Gene ID | 328789 |
| Rat Swissprot No. | Q5PPI7 |
| 特异性 | endogenous |
| 稀释度 | WB 1:1000-1:2500; |
| 参考分子量 | MW(Observed):24kDa |
| 预测分子量 | MW(Calculated):24kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The protein encoded by the LHFPL5 gene is a tetraspan membrane protein that is specifically expressed in auditory and vestibular hair cells. It localizes to the tips of stereocilia and forms an essential component of the mechanotransduction apparatus, which converts mechanical sound vibrations into electrical signals. Mutations in this gene cause autosomal recessive nonsyndromic deafness. |
| 细胞定位 | Cell membrane ; Multi-pass membrane protein . Efficient localization to the plasma membrane requires the presence of PCDH15. . |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cell membrane ; Multi-pass membrane protein . Efficient localization to the plasma membrane requires the presence of PCDH15. . |
| 组织表达 | Inner ear, Brain, Retina, Glioma, Neuroblastoma, Medulloblastoma |
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