| 别名 | Transmembrane protein 161B、FLB3342、PRO1313 |
| 基因名称 | TMEM161B |
| 蛋白名称 | Transmembrane protein 161B |
| 推荐应用 | |
| 反应物种 | Human,Mouse |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 153396 |
| Human Swissprot No. | Q8NDZ6 |
| Mouse Gene ID | 71900 |
| Mouse Swissprot No. | Q80X71 |
| 特异性 | endogenous |
| 稀释度 | WB 1:1000-1:2500;IP 1:50-1:200; |
| 参考分子量 | MW(Observed):54kDa |
| 预测分子量 | MW(Calculated):54kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Enables ATPase binding activity. Involved in dendrite morphogenesis and lysosome localization. Located in endosome and lysosomal membrane. Implicated in hypomyelinating leukodystrophy 16. [provided by Alliance of Genome Resources, Apr 2025] |
| 细胞定位 | SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q7SY10}; Multi-pass membrane protein {ECO:0000255}. |
| 功能 | FUNCTION: Essential for maintaining normal cardiac rhythm in the developing heart and for neonatal survival (By similarity). Inhibits potassium and calcium currents in the cardiomyocytes, this assists in timely action potential repolarization and thereby maintains normal cardiac rhythm (By similarity). {ECO:0000250|UniProtKB:Q8C2L6}. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q7SY10}; Multi-pass membrane protein {ECO:0000255}. |
| 组织表达 | Brain, Heart, Kidney, Glioma, Lung cancer, Breast cancer |
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