| 别名 | Transmembrane protein 248、C7orf42、TMEM248、FLJ10099、FLJ13090、LOC55069、UPF0458 protein C7orf42 |
| 基因名称 | C7orf42 |
| 蛋白名称 | TM248 |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 55069 |
| Human Swissprot No. | Q9NWD8 |
| Mouse Gene ID | 71667 |
| Mouse Swissprot No. | Q3TBN1 |
| Rat Gene ID | 288616 |
| Rat Swissprot No. | Q6AY76 |
| 特异性 | endogenous |
| 稀释度 | WB 1:1000-1:2500;FC 1:100-1:500; |
| 参考分子量 | MW(Observed):35kDa |
| 预测分子量 | MW(Calculated):35kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The protein encoded by the C7orf42 gene is a centrosome and mitotic spindle-associated protein. It localizes to centrosomes during interphase and to spindle poles and kinetochores during mitosis, where it regulates spindle assembly, chromosome alignment, and cytokinesis. It plays critical roles in cell cycle progression and maintenance of genomic stability. Several transcript variants encoding different isoforms have been identified for this gene. |
| 细胞定位 | Membrane ; Multi-pass membrane protein . |
| 功能 | similarity:Belongs to the UPF0458 family., |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Membrane ; Multi-pass membrane protein . |
| 组织表达 | Liver, Kidney, Heart, Hepatocellular carcinoma, Colon cancer, Lung cancer |
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