| 别名 | GZMK;TRYP2;Granzyme K;Fragmentin-3;Granzyme-3;NK-tryptase-2;NK-Tryp-2 |
| 基因名称 | Granzyme K |
| 蛋白名称 | Granzyme K |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 3003 |
| Human Swissprot No. | P49863 |
| Mouse Gene ID | 14945 |
| Mouse Swissprot No. | O35205 |
| Rat Gene ID | 29165 |
| Rat Swissprot No. | P49864 |
| 特异性 | endogenous |
| 稀释度 | WB 1:500-1:2000;IF 1:50-1:200;ELISA 1:5000-1:20000; |
| 参考分子量 | Mw(Observed):28KD |
| 预测分子量 | MW(Calculated):29KD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes. [provided by RefSeq, Jul 2008], |
| 细胞定位 | Secreted. Cytoplasmic granule. |
| 功能 | similarity:Belongs to the peptidase S1 family. Granzyme subfamily.,similarity:Contains 1 peptidase S1 domain.,tissue specificity:Expressed in lung, spleen, thymus and peripheral blood leukocytes., |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Secreted. Cytoplasmic granule. |
| 组织表达 | Expressed in lung, spleen, thymus and peripheral blood leukocytes. |
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