| 别名 | KCTD3;BTB/POZ domain-containing protein KCTD3 ;Renal carcinoma antigen NY-REN-45; |
| 基因名称 | KCTD3 |
| 蛋白名称 | BTB/POZ domain-containing protein KCTD3;Renal carcinoma antigen NY-REN-45; |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 51133 |
| Human Swissprot No. | Q9Y597 |
| Mouse Gene ID | 226823 |
| Mouse Swissprot No. | Q8BFX3 |
| 特异性 | endogenous |
| 稀释度 | WB 1:1000-1:2500； |
| 参考分子量 | MW(Observed):90kD |
| 预测分子量 | MW(Calculated):90kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene encodes a member of the potassium channel tetramerization-domain containing (KCTD) protein family. Members of this protein family regulate the biophysical characteristics of ion channels. In mouse, this protein interacts with hyperpolarization-activated cyclic nucleotide-gated channel complex 3 and enhances its cell surface expression and current density. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016], |
| 细胞定位 | Cell membrane. |
| 功能 | Accessory subunit of potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (HCN3) up-regulating its cell-surface expression and current density without affecting its voltage dependence and kinetics. {ECO:0000250|UniProtKB:Q8BFX3}. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cell membrane. |
| 组织表达 | Broadly expressed in normal tissues. {ECO:0000269|PubMed:10508479}. |
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