| 别名 | DHRS1;SDR19C1;Dehydrogenase/reductase SDR family member 1 ;Short chain dehydrogenase/reductase family 19C member 1;Protein SDR19C1; |
| 基因名称 | DHRS1 |
| 蛋白名称 | Dehydrogenase/reductase SDR family member 1;Short chain dehydrogenase/reductase family 19C member 1;Protein SDR19C1; |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 115817 |
| Human Swissprot No. | Q96LJ7 |
| Mouse Gene ID | 52585 |
| Mouse Swissprot No. | Q99L04 |
| 特异性 | endogenous |
| 稀释度 | WB 1:1000-1:2500； |
| 参考分子量 | MW(Observed):34kD |
| 预测分子量 | MW(Calculated):34kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family. The encoded enzyme contains a conserved catalytic domain and likely functions as an oxidoreductase. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2008], |
| 细胞定位 | Endoplasmic reticulum. Note=May be attached to the ER membrane by its C-terminus segment.. |
| 功能 | NADPH-dependent oxidoreductase which catalyzes the reduction of steroids (estrone, androstene-3,17-dione and cortisone) as well as prostaglandin E1, isatin and xenobiotics in vitro (PubMed:30031147). May have a role in steroid and/or xenobiotic metabolism (PubMed:30031147). {ECO:0000269|PubMed:30031147}. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Endoplasmic reticulum. Note=May be attached to the ER membrane by its C-terminus segment.. |
| 组织表达 | Detected in heart, liver, adrenal glands, and at low levels in skeletal muscle, kidney, pancreas and brain. {ECO:0000269|PubMed:12153138, ECO:0000269|PubMed:30031147}. |
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