| 别名 | MOB kinase activator 1A;Mob1 alpha;Mob1A;Mob1 homolog 1B;Mps one binder kinase activator-like 1B; |
| 基因名称 | MOB1 |
| 蛋白名称 | MOB1 (Thr12) |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat, |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 55233 |
| Human Swissprot No. | Q9H8S9 |
| Mouse Gene ID | 232157 |
| Mouse Swissprot No. | Q921Y0 |
| Rat Gene ID | 297387 |
| Rat Swissprot No. | Q3T1J9 |
| 特异性 | endogenous |
| 稀释度 | WB 1:1000-1:2500; |
| 参考分子量 | MW(Observed):24kD |
| 预测分子量 | MW(Calculated):24kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The protein encoded by this gene is a component of the Hippo signaling pathway, which controls organ size and tumor growth by enhancing apoptosis. Loss of the encoded protein results in cell proliferation and cancer formation. The encoded protein is also involved in the control of microtubule stability during cytokinesis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015], |
| 细胞定位 | Cytoplasm, Nucleus |
| 功能 | Function:Stimulates the kinase activity of STK38 and STK38L.,PTM:Phosphorylated.,similarity:Belongs to the MOB1/phocein family.,subunit:Binds STK38 and STK38L., |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm, Nucleus |
| 组织表达 | Adrenal gland, bone marrow, brain, placenta, prostate, salivary gland, skeletal muscle, testis, thymus, thyroid gland, heart, spinal cord, fetal brain and fetal liver. |
| 研究领域 | >>Hippo signaling pathway;>>Hippo signaling pathway - multiple species |