| 别名 | Eukaryotic translation initiation factor 4B;eIF-4B; |
| 基因名称 | EIF4B |
| 蛋白名称 | Eif4b |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 1975 |
| Human Swissprot No. | P23588 |
| Mouse Gene ID | 75705 |
| Mouse Swissprot No. | Q8BGD9 |
| 特异性 | endogenous |
| 稀释度 | WB 1:1000-1:5000；ELISA 1:5000-1:20000 |
| 参考分子量 | MW(Observed):80kD |
| 预测分子量 | MW(Calculated):69kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | cRequired for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Self-associates and interacts with EIF3 p170 subunit. |
| 细胞定位 | cytosol,polysome,eukaryotic translation initiation factor 4F complex,dendrite,neuronal cell body, |
| 功能 | Function:Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Self-associates and interacts with EIF3 p170 subunit., |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | cytosol,polysome,eukaryotic translation initiation factor 4F complex,dendrite,neuronal cell body, |
| 组织表达 | Adipose tissue,Brain,Cervix carcinoma,Epithelium,Liver,Lung |
| 研究领域 | >>mTOR signaling pathway;>>PI3K-Akt signaling pathway;>>Proteoglycans in cancer |
周一至周日 8:00-18:00
