| 别名 | GSK3A;Glycogen synthase kinase-3 alpha;GSK-3 alpha;Serine/threonine-protein kinase GSK3A;GSK3B;Glycogen synthase kinase-3 beta;GSK-3 beta;Serine/threonine-protein kinase GSK3B |
| 基因名称 | GSK3A/GSK3B |
| 蛋白名称 | Glycogen synthase kinase-3 alpha/beta |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat, |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 2931 |
| Human Swissprot No. | P49840;P49841 |
| Mouse Gene ID | 606496;56637 |
| Rat Gene ID | 50686;84027 |
| Rat Swissprot No. | P18265;P18266 |
| 特异性 | endogenous |
| 稀释度 | IHC 1:400-1:800;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200; |
| 参考分子量 | MW(Observed):51kD,47kD |
| 预测分子量 | MW(Calculated):51kD,47kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | glycogen synthase kinase 3 alpha(GSK3A) Homo sapiens This gene encodes a multifunctional Ser/Thr protein kinase that is implicated inThe control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role inThe WNT and PI3K signaling pathways, as well as regulatesThe production of beta-amyloid peptides associated with Alzheimer's disease. [provided by RefSeq, Oct 2011], |
| 细胞定位 | Cytoplasm |
| 功能 | Catalytic activity:ATP + [tau protein] = ADP + [tau protein] phosphate.,Function:Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer., |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm |
| 组织表达 | Brain,Eye,Foreskin,Lung,Pancreas,Platelet,Testis, |
| 研究领域 | >>Chemokine signaling pathway;>>Dopaminergic synapse;>>Non-alcoholic fatty liver disease;>>Shigellosis |
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