| 别名 | CD99 antigen;12E7;E2 antigen;Protein MIC2;T-cell surface glycoprotein E2;CD antigen CD99; |
| 基因名称 | CD99 |
| 蛋白名称 | CD99 |
| 推荐应用 | |
| 反应物种 | Human, |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 4267 |
| Human Swissprot No. | P14209 |
| 特异性 | endogenous |
| 稀释度 | IHC 1:200-1:1000;WB 1:1000-1:2500;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200, |
| 参考分子量 | MW(Observed):30kD |
| 预测分子量 | MW(Calculated):19kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. There is a related pseudogene located immediately adjacent to this locus. [provided by RefSeq, Mar 2016], |
| 细胞定位 | Membrane |
| 功能 | Function:Involved in T-cell adhesion processes. It is involved in spontaneous rosette formation with erythrocytes.,miscellaneous:The gene encoding for this protein is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes.,PTM:Extensively O-glycosylated.,similarity:Belongs to the CD99 family., |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Membrane |
| 组织表达 | Membranous |
| 研究领域 | >>Cell adhesion molecules;>>Leukocyte transendothelial migration |
周一至周日 8:00-18:00
