| 别名 | Fatty acid-binding protein, adipocyte;Adipocyte lipid-binding protein;ALBP;Adipocyte-type fatty acid-binding protein;A-FABP;AFABP;Fatty acid-binding protein 4; |
| 基因名称 | FABP4 |
| 蛋白名称 | A-FABP |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat, |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 2167 |
| Human Swissprot No. | P15090 |
| Mouse Gene ID | 11770 |
| Mouse Swissprot No. | P04117 |
| Rat Swissprot No. | P70623 |
| 特异性 | endogenous |
| 稀释度 | IHC 1:200-1000;WB 1:1000-1:2500;IF 1:200-1000;ELISA 1:5000-20000;IP 1:50-200 |
| 参考分子量 | MW(Observed):15kD |
| 预测分子量 | MW(Calculated):15kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | FABP4 encodes the fatty acid binding protein found in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Jul 2008], |
| 细胞定位 | Cytoplasm |
| 功能 | Domain:Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.,Function:Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus.,similarity:Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.,subcellular location:Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export.,subunit:Homodimer. Interacts with PPARG (By similarity). Monomer., |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm |
| 组织表达 | White adipose tissue, Brown adipose tissue, Liver, Macrophages, Liposarcoma, Breast cancer, Ovarian cancer |
| 研究领域 | >>PPAR signaling pathway;>>Regulation of lipolysis in adipocytes |
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