| 别名 | DDX9;LKP;NDH2 |
| 基因名称 | DHX9 |
| 蛋白名称 | ATP-dependent RNA helicase A (RHA) (DEAH box protein 9) (Leukophysin) (LKP) (Nuclear DNA helicase II) (NDH II) |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | Q08211 |
| Mouse Gene ID | 13211 |
| Mouse Swissprot No. | O70133 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:200-1:1000;WB 1:2000-1:10000;IF-P/IF-F/IF-ICC 1:200-1:1000;ELISA 1:5000-1:20000 |
| 参考分子量 | 141kDa |
| 预测分子量 | 141kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 细胞定位 | Nucleus . Nucleus , nucleoplasm . Nucleus , nucleolus . Cytoplasm . Cytoplasm , cytoskeleton , microtubule organizing center , centrosome . Nucleoplasmic shuttling protein (PubMed:10198287 , PubMed:16375861 , PubMed:10207077 , PubMed:9162007) . Its nuclear import involves the nucleocytoplasmic transport receptor Importin alpha/Importin beta receptor pathway in a Ran-dependent manner (PubMed:16375861) . In interphase , localizes in nuclear stress granules and at perichromatin fibrils and in cytoplasmic ribonucleoprotein granules (PubMed:10198287) . Colocalizes with WRN and H2AX at centrosomes in a microtubule-dependent manner following DNA damaging agent treatment (PubMed:17498979) . Excluded from the mitotic nucleus as early as prophase and re-entered the nucleus at telophase (PubMed:10198287) . Recruited in diffuse and discrete intranuclear foci (GLFG-body) in a NUP98-dependent manner (PubMed:28221134) . Colocalizes with SP7 in the nucleus (PubMed:17303075) . Colocalizes with ACTB at nuclear actin filaments inside the nucleus or at the nuclear pore (PubMed:11687588) . Colocalizes with HNRNPC at nuclear ribonucleoprotein complex proteins in the nucleus (PubMed:11687588) . Localized in cytoplasmic mRNP granules containing untranslated mRNAs (PubMed:17289661) . . |
| 纯化 | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Clonality | Monoclonal |
| 细胞定位 | Nucleus . Nucleus , nucleoplasm . Nucleus , nucleolus . Cytoplasm . Cytoplasm , cytoskeleton , microtubule organizing center , centrosome . Nucleoplasmic shuttling protein (PubMed:10198287 , PubMed:16375861 , PubMed:10207077 , PubMed:9162007) . Its nuclear import involves the nucleocytoplasmic transport receptor Importin alpha/Importin beta receptor pathway in a Ran-dependent manner (PubMed:16375861) . In interphase , localizes in nuclear stress granules and at perichromatin fibrils and in cytoplasmic ribonucleoprotein granules (PubMed:10198287) . Colocalizes with WRN and H2AX at centrosomes in a microtubule-dependent manner following DNA damaging agent treatment (PubMed:17498979) . Excluded from the mitotic nucleus as early as prophase and re-entered the nucleus at telophase (PubMed:10198287) . Recruited in diffuse and discrete intranuclear foci (GLFG-body) in a NUP98-dependent manner (PubMed:28221134) . Colocalizes with SP7 in the nucleus (PubMed:17303075) . Colocalizes with ACTB at nuclear actin filaments inside the nucleus or at the nuclear pore (PubMed:11687588) . Colocalizes with HNRNPC at nuclear ribonucleoprotein complex proteins in the nucleus (PubMed:11687588) . Localized in cytoplasmic mRNP granules containing untranslated mRNAs (PubMed:17289661) . . |
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