| 别名 | TIP49A;INO80H;NMP238;TIP49;TIP49A |
| 基因名称 | RUVBL1 |
| 蛋白名称 | RuvB-like 1 |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | Q9Y265 |
| Mouse Gene ID | 56505 |
| Mouse Swissprot No. | P60122 |
| Rat Gene ID | 65137 |
| Rat Swissprot No. | P60123 |
| 特异性 | Endogenous |
| 稀释度 | IHC-P 1:200-1:1000;WB 1:2000-1:10000;IF-P/IF-F/IF-ICC 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200 |
| 参考分子量 | 55kDa |
| 预测分子量 | 50kDa |
| 运输及保存条件 | Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene encodes a protein that has both DNA-dependent ATPase and DNA helicase activities and belongs to the ATPases associated with diverse cellular activities (AAA+) protein family. The encoded protein associates with several multisubunit transcriptional complexes and with protein complexes involved in both ATP-dependent remodeling and histone modification. Alternate splicing results in multiple transcript variants. [provided by RefSeq , Jan 2016] , |
| 细胞定位 | Nucleus matrix. Nucleus , nucleoplasm. Cytoplasm . Membrane . Cytoplasm , cytoskeleton , microtubule organizing center , centrosome. Dynein axonemal particle . Mainly localized in the nucleus , associated with nuclear matrix or in the nuclear cytosol , although it is also present in the cytoplasm and associated with the cell membranes. In prophase and prometaphase it is located at the centrosome and the branching microtubule spindles. After mitotic nuclear membrane disintigration it accumulates at the centrosome and sites of tubulin polymerization. As cells pass through metaphase and into telophase it is located close to the centrosome at the early phase of tubulin polymerization. In anaphase it accumulates at the zone of tubule interdigitation. In telophase it is found at polar tubule overlap , and it reappears at the site of chromosomal decondensation in the daughter cells. |
| 纯化 | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Clonality | Monoclonal |
| 细胞定位 | Nucleus matrix. Nucleus , nucleoplasm. Cytoplasm . Membrane . Cytoplasm , cytoskeleton , microtubule organizing center , centrosome. Dynein axonemal particle . Mainly localized in the nucleus , associated with nuclear matrix or in the nuclear cytosol , although it is also present in the cytoplasm and associated with the cell membranes. In prophase and prometaphase it is located at the centrosome and the branching microtubule spindles. After mitotic nuclear membrane disintigration it accumulates at the centrosome and sites of tubulin polymerization. As cells pass through metaphase and into telophase it is located close to the centrosome at the early phase of tubulin polymerization. In anaphase it accumulates at the zone of tubule interdigitation. In telophase it is found at polar tubule overlap , and it reappears at the site of chromosomal decondensation in the daughter cells. |
周一至周日 8:00-18:00
